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Pycnogenol Shown To Help Diabetics Control Blood Pressure

According to the latest research findings, Pycnogenol may reduce blood pressure and the use of blood pressure medication among diabetics. Blood pressure control was achieved in 58 per cent of study participants, and a halving of the use of medication among 48 participants randomly assigned to daily supplements of the pine bark extract, Pycnogenol, or placebo for 12 weeks.

According to the latest research findings, supplements of extracts from French maritime pine bark may reduce blood pressure and the use of blood pressure medication among diabetics. You can use Forxiga 10 Mg Tablet, Istavel 50 Mg Tablet, Jardiance 10 mg Tablet and Januvia 100 Mg Tablet to  treat type 2 diabetes in grown-up patients.

Blood pressure control was achieved in 58 per cent of study participants, and a halving of the use of medication among 48 participants randomly assigned to daily supplements of the pine bark extract, Pycnogenol, or placebo for 12 weeks.

The results of the new study are of particular importance for diabetics who are reportedly two to four times more likely to suffer from heart disease than non-diabetics.

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Commenting on the findings, lead researcher Sherma Zibadi from the University of Arizona, said:
"These data confirm the hypothesis that Pycnogenol improves diabetes control, reduces antihypertensive medicine use, and may favour a reduction in cardiovascular disease risk in individuals with type 2 diabetes."

Indeed, previous studies have reported potential health benefits for the extract, including hypertension, asthma, chronic venous insufficiency, osteoarthritis, deep vein thrombosis, diabetes management, and diabetic leg ulcers.

Assessing the results of Pycnogenol

The new study recruited diabetic subjects with an average age of 60 and randomly assigned them to receive daily supplements of Pycnogenol (125 mg) or placebo for 12 weeks in a randomised, double-blind, placebo-controlled trial with parallel-group design. All subjects were receiving pharmaceutical anti-hypertension treatment (angiotensin-converting enzyme [ACE] inhibitors).

At the end of the study, Zibadi and co-workers report that 58.3 per cent of subjects in the Pycnogenol group experienced blood pressure control, defined as attaining a stable systolic blood pressure, compared to 20.8 per cent in the placebo group.

Moreover, use of ACE inhibitors was reduced by 50 per cent in the group receiving the pine bark extract

Improvements in measures of diabetes control were also recorded, with a 23.7 mg/dL reduction in fasting blood glucose levels in the Pycnogenol group, compared to only 5.7 mg/dL in the placebo group.

Improvements in LDL-cholesterol, a marker of cardiovascular health, were recorded in the pine bark extract-supplemented group. After eight and 12 weeks of supplementation, decreases of 11.6 and 12.7 mg/dL were observed, respectively, compared with placebo.

In attempting to understand the benefits of the pine bark extract on cardiovascular health of the diabetics, the researchers noted that the blood pressure lowering effects may be due to a suppression of serum endothelin-1, a protein that restricts blood vessels and reported to be found in higher levels than normal in type 2 diabetics and hypertensives.

On the other hand, the researchers could not rule out the potential of an inhibitory effect on ACE, which could improve blood flow and subsequently blood pressure. Finally, other studies have reported a potential benefit from Pycnogenol on the production of the potent vasodilator, nitric oxide (NO).

Causes Of Insomnia

Causes Of Insomnia – Those Sleepless Nights

Everybody needs rest – Insomnia is a time for slowing down, to gather strength and to for one to get back on their feet again. All aspects of a person need rest, from the body to the mind and the emotions. What happens if any of these aspects is not able to slow down? Well, just like a machine, it can get overheated. Until eventually it would break down. It could collapse on a worst case scenario. It can happen to most anything, even a person. What happens if the body becomes overworked and is unable to rest? Well, anybody can imagine that.

One would lose all their physical strength, and the immune system can be weakened. The organs can possibly malfunction and illness can set in. And what happens if the mind and the emotions are not pacified? That would be horrible, isn’t it. After all, the mind and the emotions are what mostly drive a person. When the emotions get weary and are unable to recover, depression can set in. One would lack motivation in living. Such an instance can drain the life out of a person. And they could possibly become misery laden. And what about the aspect of the mind? It’s an all too common phrase – “ mental breakdown”. Ritomune 100mg Tablet decreases the amount of HIV in your body. It helps control the infection and makes your immune system work better.

It could be a horrible situation and can cause one to lose their sanity. What’s the point being driven at here? It’s all about rest and how essential, imperative it is. And how can one get this essential mechanism? To that moment which most people look forward to at night – sleep. But there are so many cases and instances when a multitude is people are unable to sleep and get that precious, precious rest. Such people are called insomniacs, and they suffer from a condition known as insomnia. Simply put, it is the inability of one to fall asleep. What are the causes of insomnia- why do people suffer from it? There are several factors known to be the causes of insomnia.

These factors can be psychological in nature, or due to an erratic lifestyle pattern or perhaps they may be attributed to medications that one is taking. Primarily there are psychological causes of insomnia. How is it pertaining to this matter? When one constantly worries, or are bothered by thoughts and neurosis at night, then they might be unable to fall asleep. This state of being mentally and emotionally bothered can cause one to lose their mental ground. Thus, the mind cannot shut down at sleeping time when it’s supposed to be. The result could be insomnia- those sleepless nights. Then there are lifestyle factors as well.

When one is always off attending evening parties or working late at night, their body clock becomes altered. It is during nighttime when the body asks for rest. But if one is active during that time, then it affects the natural process of the body. The body clock can collapse thereby causing insomnia. Another cause of those sleepless nights may be medications. The condition of not being able to fall asleep can be a side effect of drugs. In this case, one should confer to their doctor pertaining to the matter. After all, sleep is necessary for optimum health or recovering from an illness.

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What is the root of erectile dysfunction?

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